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Biochemical characterization of RGS14: RGS14 activity towards G-protein α subunits is independent of its binding to Rap2A

RGS (regulators of G-protein signalling) modulate signalling by acting as GAPs (GTPase-activating proteins) for α subunits of heterotrimeric G-proteins. RGS14 accelerates GTP hydrolysis by G(iα) family members through its RGS domain and suppresses guanine nucleotide dissociation from G(iα1) and G(iα...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mittal, Vivek, Linder, Maurine E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Portland Press Ltd. 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1386029/
https://ncbi.nlm.nih.gov/pubmed/16246175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051086
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