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Biochemical characterization of RGS14: RGS14 activity towards G-protein α subunits is independent of its binding to Rap2A
RGS (regulators of G-protein signalling) modulate signalling by acting as GAPs (GTPase-activating proteins) for α subunits of heterotrimeric G-proteins. RGS14 accelerates GTP hydrolysis by G(iα) family members through its RGS domain and suppresses guanine nucleotide dissociation from G(iα1) and G(iα...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1386029/ https://ncbi.nlm.nih.gov/pubmed/16246175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051086 |
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