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RGS2/G0S8 is a selective inhibitor of Gqα function

RGS (regulators of G protein signaling) proteins are GTPase activating proteins that inhibit signaling by heterotrimeric G proteins. All RGS proteins studied to date act on members of the Giα family, but not Gsα or G12α. RGS4 regulates Giα family members and Gqα. RGS2 (G0S8) is exceptional because t...

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Detalhes bibliográficos
Main Authors: Heximer, Scott P., Watson, Ned, Linder, Maurine E., Blumer, Kendall J., Hepler, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC24991/
https://ncbi.nlm.nih.gov/pubmed/9405622
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