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RGS2/G0S8 is a selective inhibitor of Gqα function

RGS (regulators of G protein signaling) proteins are GTPase activating proteins that inhibit signaling by heterotrimeric G proteins. All RGS proteins studied to date act on members of the Giα family, but not Gsα or G12α. RGS4 regulates Giα family members and Gqα. RGS2 (G0S8) is exceptional because t...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Heximer, Scott P., Watson, Ned, Linder, Maurine E., Blumer, Kendall J., Hepler, John R.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1997
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24991/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9405622/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.26.14389
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