Identification of the anti-inflammatory protein tristetraprolin as a hyperphosphorylated protein by mass spectrometry and site-directed mutagenesis

Tristetraprolin (TTP) is a zinc-finger protein that binds to AREs (AU-rich elements) within certain mRNAs and causes destabilization of those mRNAs. Mice deficient in TTP develop a profound inflammatory syndrome with erosive arthritis, autoimmunity and myeloid hyperplasia. Previous studies showed th...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Cao, Heping, Deterding, Leesa J., Venable, John D., Kennington, Elizabeth A., Yates, John R., Tomer, Kenneth B., Blackshear, Perry J.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1386027/
https://ncbi.nlm.nih.gov/pubmed/16262601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051316
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados