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A biotinylated analog of the spin-trap DMPO for the detection of low abundance protein radicals by mass spectrometry

Protein radicals are implicated in oxidative stress and are associated with a wide range of diseases and disorders. In the present work, we describe the specific application of a newly synthesized nitrone spin trap, Bio-SS-DMPO, for the detection of these highly reactive species by mass spectrometry...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Lardinois, Olivier M., Chatterjee, Saurabh, Mason, Ronald P., Tomer, Kenneth B., Deterding, Leesa J.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980571/
https://ncbi.nlm.nih.gov/pubmed/20957988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac1023183
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