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A biotinylated analog of the spin-trap DMPO for the detection of low abundance protein radicals by mass spectrometry

Protein radicals are implicated in oxidative stress and are associated with a wide range of diseases and disorders. In the present work, we describe the specific application of a newly synthesized nitrone spin trap, Bio-SS-DMPO, for the detection of these highly reactive species by mass spectrometry...

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Detalhes bibliográficos
Main Authors: Lardinois, Olivier M., Chatterjee, Saurabh, Mason, Ronald P., Tomer, Kenneth B., Deterding, Leesa J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980571/
https://ncbi.nlm.nih.gov/pubmed/20957988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac1023183
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