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A biotinylated analog of the spin-trap DMPO for the detection of low abundance protein radicals by mass spectrometry
Protein radicals are implicated in oxidative stress and are associated with a wide range of diseases and disorders. In the present work, we describe the specific application of a newly synthesized nitrone spin trap, Bio-SS-DMPO, for the detection of these highly reactive species by mass spectrometry...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2980571/ https://ncbi.nlm.nih.gov/pubmed/20957988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac1023183 |
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