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Artificial human telomeres from DNA nanocircle templates
Human telomerase is a reverse-transcriptase enzyme that synthesizes the multikilobase repeating hexamer telomere sequence (TTAGGG)(n) at the ends of chromosomes. Here we describe a designed approach to mimicry of telomerase, in which synthetic DNA nanocircles act as essentially infinite catalytic te...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2002
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC138546/ https://ncbi.nlm.nih.gov/pubmed/12444252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.252396199 |
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