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Mutational analysis of human eIF4AIII identifies regions necessary for exon junction complex formation and nonsense-mediated mRNA decay
The exon junction complex (EJC) is deposited on mRNAs by the process of pre-mRNA splicing and is a key effecter of downstream mRNA metabolism. We previously demonstrated that human eIF4AIII, which is essential for nonsense-mediated mRNA decay (NMD), constitutes at least part of the RNA-binding platf...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Copyright 2006 by RNA Society
2006
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1383576/ https://ncbi.nlm.nih.gov/pubmed/16495234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2190706 |
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