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Iron-responsive degradation of iron-regulatory protein 1 does not require the Fe–S cluster
The generally accepted role of iron-regulatory protein 1 (IRP1) in orchestrating the fate of iron-regulated mRNAs depends on the interconversion of its cytosolic aconitase and RNA-binding forms through assembly/disassembly of its Fe–S cluster, without altering protein abundance. Here, we show that I...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1383537/ https://ncbi.nlm.nih.gov/pubmed/16424901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600954 |
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