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Mice with altered KCNQ4 K(+) channels implicate sensory outer hair cells in human progressive deafness
KCNQ4 is an M-type K(+) channel expressed in sensory hair cells of the inner ear and in the central auditory pathway. KCNQ4 mutations underlie human DFNA2 dominant progressive hearing loss. We now generated mice in which the KCNQ4 gene was disrupted or carried a dominant negative DFNA2 mutation. Alt...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1383535/ https://ncbi.nlm.nih.gov/pubmed/16437162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600951 |
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