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Mechanisms contributing to synaptic Ca(2+) signals and their heterogeneity in hair cells

Sound coding at hair cell ribbon synapses is tightly regulated by Ca(2+). Here, we used patch-clamp, fast confocal Ca(2+) imaging and modeling to characterize synaptic Ca(2+) signaling in cochlear inner hair cells (IHCs) of hearing mice. Submicrometer fluorescence hotspots built up and collapsed at...

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Detalhes bibliográficos
Main Authors: Frank, Thomas, Khimich, Darina, Neef, Andreas, Moser, Tobias
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657422/
https://ncbi.nlm.nih.gov/pubmed/19246382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813213106
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