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KCNQ4, a K(+) channel mutated in a form of dominant deafness, is expressed in the inner ear and the central auditory pathway

Mutations in the potassium channel gene KCNQ4 underlie DFNA2, an autosomal dominant form of progressive hearing loss in humans. In the mouse cochlea, the transcript has been found exclusively in the outer hair cells. By using specific antibodies, we now show that KCNQ4 is situated at the basal membr...

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Detalhes bibliográficos
Main Authors: Kharkovets, Tatjana, Hardelin, Jean-Pierre, Safieddine, Saaid, Schweizer, Michaela, El-Amraoui, Aziz, Petit, Christine, Jentsch, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC18242/
https://ncbi.nlm.nih.gov/pubmed/10760300
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