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Divided-dose kinetics of mefloquine in man.

The kinetics of mefloquine was investigated following oral divided-doses in 10 healthy Caucasian volunteers. They received 500 or 750 mg followed by 500 mg 8 h later. Unchanged mefloquine (M) and its carboxylic acid metabolite (MM) were measured in whole blood and plasma for 50 days by h.p.l.c. Maxi...

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Detalhes bibliográficos
Main Authors: Franssen, G, Rouveix, B, Lebras, J, Bauchet, J, Verdier, F, Michon, C, Bricaire, F
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1379902/
https://ncbi.nlm.nih.gov/pubmed/2789071
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