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Single-dose kinetics of mefloquine in Brazilian male subjects

Ten male subjects from a region of the state of Pará, Brazil, where malaria is endemic received a single oral dose of 1000 mg mefloquine. The plasma levels of the drug and of its metabolite, 2,8-bis(trifluoromethyl)-4-quinolinecarboxylic acid, were determined densitometrically on thin-layer chromato...

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Detalhes bibliográficos
Main Authors: de Souza, J. M., Heizmann, P., Schwartz, D. E.
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2491007/
https://ncbi.nlm.nih.gov/pubmed/3499250
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