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Effect of dose on the glucuronidation and sulphation kinetics of diflunisal in man: single dose studies.

1. The effect of dose (100 mg, 250 mg, 500 mg, 750 mg and 1000 mg) on the glucuronidation and sulphation of diflunisal was studied in six healthy volunteers. 2. Total urinary recovery ranged from 78.9 +/- 11.9% to 91.5 +/- 18.7% of the administered dose. Urinary recovery (normalized for total urinar...

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Detalles Bibliográficos
Main Authors: Loewen, G R, Herman, R J, Ross, S G, Verbeeck, R K
Formato: Artigo
Idioma:Inglês
Publicado: 1988
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1386496/
https://ncbi.nlm.nih.gov/pubmed/3203058
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