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The pharmacokinetics of mefloquine in man: lack of effect of mefloquine on antipyrine metabolism.

A method is described for the determination of the new antimalarial agent, mefloquine, in plasma and urine. After oral administration of 750 mg mefloquine to six volunteers, absorption, was apparently slow, with plasma mefloquine concentrations at 24 h (559 +/- 181 ng ml-1; mean +/- s.d.) higher tha...

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Main Authors: Rivière, J H, Back, D J, Breckenridge, A M, Howells, R E
格式: Artigo
語言:Inglês
出版: 1985
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1400721/
https://ncbi.nlm.nih.gov/pubmed/3878153
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