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The pharmacokinetics of mefloquine in man: lack of effect of mefloquine on antipyrine metabolism.

A method is described for the determination of the new antimalarial agent, mefloquine, in plasma and urine. After oral administration of 750 mg mefloquine to six volunteers, absorption, was apparently slow, with plasma mefloquine concentrations at 24 h (559 +/- 181 ng ml-1; mean +/- s.d.) higher tha...

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Dettagli Bibliografici
Autori principali: Rivière, J H, Back, D J, Breckenridge, A M, Howells, R E
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1985
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1400721/
https://ncbi.nlm.nih.gov/pubmed/3878153
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