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A synthetic HIV-1 Rev inhibitor interfering with the CRM1-mediated nuclear export
The HIV-1 Rev protein is an essential regulator of the HIV-1 mRNA expression that promotes the export of unspliced and partially spliced mRNA. The export receptor for the leucine-rich nuclear export signal (NES) of Rev has recently been recognized as CRM1. We identified a low molecular weight compou...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC137902/ https://ncbi.nlm.nih.gov/pubmed/12374846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.212285299 |
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