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Nucleocytoplasmic Distribution of the Ovalbumin Serpin PI-9 Requires a Nonconventional Nuclear Import Pathway and the Export Factor Crm1
Proteinase inhibitor 9 (PI-9) is a human serpin present in the cytoplasm of cytotoxic lymphocytes and epithelial cells. It inhibits the cytotoxic lymphocyte granule proteinase granzyme B (graB) and is thought to protect cytotoxic lymphocytes and bystander cells from graB-mediated apoptosis. Followin...
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Autori principali: | , , , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
American Society for Microbiology
2001
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC87262/ https://ncbi.nlm.nih.gov/pubmed/11463822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.16.5396-5407.2001 |
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