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Effect of polyethylene glycol on the liquid–liquid phase transition in aqueous protein solutions

We have studied the effect of polyethylene glycol (PEG) on the liquid–liquid phase separation (LLPS) of aqueous solutions of bovine γD-crystallin (γD), a protein in the eye lens. We observe that the phase separation temperature increases with both PEG concentration and PEG molecular weight. PEG part...

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Detalles Bibliográficos
Main Authors: Annunziata, Onofrio, Asherie, Neer, Lomakin, Aleksey, Pande, Jayanti, Ogun, Olutayo, Benedek, George B.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC137855/
https://ncbi.nlm.nih.gov/pubmed/12391331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.212507199
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