Effect of polyethylene glycol on the liquid–liquid phase transition in aqueous protein solutions

We have studied the effect of polyethylene glycol (PEG) on the liquid–liquid phase separation (LLPS) of aqueous solutions of bovine γD-crystallin (γD), a protein in the eye lens. We observe that the phase separation temperature increases with both PEG concentration and PEG molecular weight. PEG part...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Annunziata, Onofrio, Asherie, Neer, Lomakin, Aleksey, Pande, Jayanti, Ogun, Olutayo, Benedek, George B.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2002
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137855/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12391331/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.212507199
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