Expanding protein universe and its origin from the biological Big Bang

The bottom-up approach to understanding the evolution of organisms is by studying molecular evolution. With the large number of protein structures identified in the past decades, we have discovered peculiar patterns that nature imprints on protein structural space in the course of evolution. In part...

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Εκδόθηκε σε:	Proc Natl Acad Sci U S A
Κύριοι συγγραφείς:	Dokholyan, Nikolay V., Shakhnovich, Boris, Shakhnovich, Eugene I.
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	National Academy of Sciences 2002
Θέματα:	Biological Sciences
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137849/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12384571/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.202497999
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