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Expanding protein universe and its origin from the biological Big Bang

The bottom-up approach to understanding the evolution of organisms is by studying molecular evolution. With the large number of protein structures identified in the past decades, we have discovered peculiar patterns that nature imprints on protein structural space in the course of evolution. In part...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Dokholyan, Nikolay V., Shakhnovich, Boris, Shakhnovich, Eugene I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2002
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137849/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12384571/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.202497999
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