Regeneration of misprimed nonribosomal peptide synthetases by type II thioesterases
Nonribosomal peptide synthetases (NRPSs) assemble structurally complex peptides from simple building blocks such as amino and carboxyl acids. Product release by macrocyclization or hydrolysis is catalyzed by a thioesterase domain that is an integrated part of the NRPS enzyme. A second thioesterase o...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2002
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137840/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12384573/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.212382199 |
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