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Regeneration of misprimed nonribosomal peptide synthetases by type II thioesterases
Nonribosomal peptide synthetases (NRPSs) assemble structurally complex peptides from simple building blocks such as amino and carboxyl acids. Product release by macrocyclization or hydrolysis is catalyzed by a thioesterase domain that is an integrated part of the NRPS enzyme. A second thioesterase o...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2002
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC137840/ https://ncbi.nlm.nih.gov/pubmed/12384573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.212382199 |
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