Defining thyrotropin-dependent and -independent steps of thyroid hormone synthesis by using thyrotropin receptor-null mice

The thyrotropin (TSH) receptor (TSHR) is a member of the heterotrimeric G protein-coupled family of receptors whose main function is to regulate thyroid cell proliferation as well as thyroid hormone synthesis and release. In this study, we generated a TSHR knockout (TSHR-KO) mouse by homologous reco...

Whakaahuatanga katoa

Ngā taipitopito rārangi puna kōrero

I whakaputaina i:	Proc Natl Acad Sci U S A
Ngā kaituhi matua:	Marians, R. C., Ng, L., Blair, H. C., Unger, P., Graves, P. N., Davies, T. F.
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	National Academy of Sciences 2002
Ngā marau:	Biological Sciences
Urunga tuihono:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137792/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12432094/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.242322099
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!