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Defining thyrotropin-dependent and -independent steps of thyroid hormone synthesis by using thyrotropin receptor-null mice

The thyrotropin (TSH) receptor (TSHR) is a member of the heterotrimeric G protein-coupled family of receptors whose main function is to regulate thyroid cell proliferation as well as thyroid hormone synthesis and release. In this study, we generated a TSHR knockout (TSHR-KO) mouse by homologous reco...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Marians, R. C., Ng, L., Blair, H. C., Unger, P., Graves, P. N., Davies, T. F.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2002
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137792/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12432094/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.242322099
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