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RAG-dependent peripheral T cell receptor diversification in CD8(+) T lymphocytes
Rearrangement of T cell receptor (TCR) genes is driven by transient expression of V(D)J recombination-activating genes (RAGs) during lymphocyte development. Immunological dogma holds that T cells irreversibly terminate RAG expression before exiting the thymus, and that all of the progeny arising fro...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC137757/ https://ncbi.nlm.nih.gov/pubmed/12432095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.242321099 |
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