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Developmental control of CD8(+) T cell–avidity maturation in autoimmune diabetes
The progression of immune responses is generally associated with an increase in the overall avidity of antigen-specific T cell populations for peptide-MHC. This is thought to result from preferential expansion of high-avidity clonotypes at the expense of their low-avidity counterparts. Since T cell...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2005
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1142112/ https://ncbi.nlm.nih.gov/pubmed/15937548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI24219 |
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