RAG-dependent peripheral T cell receptor diversification in CD8(+) T lymphocytes

Rearrangement of T cell receptor (TCR) genes is driven by transient expression of V(D)J recombination-activating genes (RAGs) during lymphocyte development. Immunological dogma holds that T cells irreversibly terminate RAG expression before exiting the thymus, and that all of the progeny arising fro...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Serra, Pau, Amrani, Abdelaziz, Han, Bingye, Yamanouchi, Jun, Thiessen, Shari J., Santamaria, Pere
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2002
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC137757/
https://ncbi.nlm.nih.gov/pubmed/12432095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.242321099
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