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Transcriptional profiling of a mouse model for Rett syndrome reveals subtle transcriptional changes in the brain
The Mecp2 gene has been shown to be mutated in most cases of human Rett syndrome, and mouse models deleted for the ortholog have been generated. Lineage-specific deletion of the gene indicated that the Rett-like phenotype is caused by Mecp2 deficiency in neurons. Biochemical evidence suggests that M...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC137752/ https://ncbi.nlm.nih.gov/pubmed/12432090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.242566899 |
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