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Quantitative analysis of fetal DNA in maternal plasma and serum: implications for noninvasive prenatal diagnosis.

We have developed a real-time quantitative PCR assay to measure the concentration of fetal DNA in maternal plasma and serum. Our results show that fetal DNA is present in high concentrations in maternal plasma, reaching a mean of 25.4 genome equivalents/ml (range 3.3-69. 4) in early pregnancy and 29...

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書誌詳細
主要な著者: Lo, Y M, Tein, M S, Lau, T K, Haines, C J, Leung, T N, Poon, P M, Wainscoat, J S, Johnson, P J, Chang, A M, Hjelm, N M
フォーマット: Artigo
言語:Inglês
出版事項: 1998
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1377040/
https://ncbi.nlm.nih.gov/pubmed/9529358
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