Quantitative analysis of fetal DNA in maternal plasma and serum: implications for noninvasive prenatal diagnosis.

We have developed a real-time quantitative PCR assay to measure the concentration of fetal DNA in maternal plasma and serum. Our results show that fetal DNA is present in high concentrations in maternal plasma, reaching a mean of 25.4 genome equivalents/ml (range 3.3-69. 4) in early pregnancy and 29...

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Main Authors: Lo, Y M, Tein, M S, Lau, T K, Haines, C J, Leung, T N, Poon, P M, Wainscoat, J S, Johnson, P J, Chang, A M, Hjelm, N M
Format: Artigo
Jezik:Inglês
Izdano: 1998
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1377040/
https://ncbi.nlm.nih.gov/pubmed/9529358
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