Quantitative analysis of fetal DNA in maternal plasma and serum: implications for noninvasive prenatal diagnosis.

We have developed a real-time quantitative PCR assay to measure the concentration of fetal DNA in maternal plasma and serum. Our results show that fetal DNA is present in high concentrations in maternal plasma, reaching a mean of 25.4 genome equivalents/ml (range 3.3-69. 4) in early pregnancy and 29...

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Detaylı Bibliyografya
Asıl Yazarlar: Lo, Y M, Tein, M S, Lau, T K, Haines, C J, Leung, T N, Poon, P M, Wainscoat, J S, Johnson, P J, Chang, A M, Hjelm, N M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1998
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1377040/
https://ncbi.nlm.nih.gov/pubmed/9529358
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