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Optimization and evaluation of T7 based RNA linear amplification protocols for cDNA microarray analysis

BACKGROUND: T7 based linear amplification of RNA is used to obtain sufficient antisense RNA for microarray expression profiling. We optimized and systematically evaluated the fidelity and reproducibility of different amplification protocols using total RNA obtained from primary human breast carcinom...

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Main Authors: Zhao, Hongjuan, Hastie, Trevor, Whitfield, Michael L, Børresen-Dale, Anne-Lise, Jeffrey, Stefanie S
格式: Artigo
語言:Inglês
出版: BioMed Central 2002
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC137577/
https://ncbi.nlm.nih.gov/pubmed/12445333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-3-31
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