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Negative autoregulation of BCL-6 is bypassed by genetic alterations in diffuse large B cell lymphomas
Thirty to forty percent of diffuse large B cell lymphomas (DLBCL) carry BCL-6 translocations that disrupt its 5′ regulatory region. This same region is also subject to somatic hypermutations, although only a small fraction of these mutations have a detectable effect on transcription. Here, we show t...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC137537/ https://ncbi.nlm.nih.gov/pubmed/12407182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.232581199 |
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