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Therapeutic targeting of the BCL6 oncogene for diffuse large B-cell lymphomas

BCL6 is a transcriptional repressor often expressed constitutively in diffuse large B-cell lymphomas (DLBCL) due to mutations of its genomic locus. BCL6 mediates aberrant survival, proliferation, genomic instability and differentiation blockade in DLBCL cells. The biochemical study of BCL6 mediated...

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Detalhes bibliográficos
Main Authors: Parekh, Samir S, Privé, Gilbert G, Melnick, Ari
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748726/
https://ncbi.nlm.nih.gov/pubmed/18452090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10428190801895345
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