Distinctive patterns of BCL6 molecular alterations and their functional consequences in different subgroups of diffuse large B-cell lymphoma

Gene expression profiling of diffuse large B-cell lymphoma (DLBCL) has revealed biologically and prognostically distinct subgroups: germinal center B-cell-like (GCB), activated B-cell-like (ABC) and primary mediastinal (PM) DLBCL. The BCL6 gene is often translocated and/or mutated in DLBCL. Therefor...

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Main Authors: Iqbal, J, Greiner, TC, Patel, K, Dave, BJ, Smith, L, Ji, J, Wright, G, Sanger, WG, Pickering, DL, Jain, S, Horsman, DE, Shen, Y, Fu, K, Weisenburger, DD, Hans, CP, Campo, E, Gascoyne, RD, Rosenwald, A, Jaffe, ES, Delabie, J, Rimsza, L, Ott, G, Müller-Hermelink, HK, Connors, JM, Vose, JM, McKeithan, T, Staudt, LM, Chan, WC
Format: Artigo
Language:Inglês
Published: 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366166/
https://ncbi.nlm.nih.gov/pubmed/17625604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.leu.2404856
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