Combined copy number and mutation analysis identifies oncogenic pathways associated with transformation of follicular lymphoma

Follicular lymphoma (FL) is typically an indolent disease, but 30-40% of FL cases transform into an aggressive lymphoma (tFL) with a poor prognosis. To identify the genetic changes that drive this transformation, we sequenced the exomes of 12 cases with paired FL and tFL biopsies, and identified 45...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Leukemia
Main Authors: Bouska, Alyssa, Zhang, Weiwei, Gong, Qiang, Iqbal, Javeed, Scuto, Anna, Vose, Julie, Ludvigsen, Maja, Fu, Kai, Weisenburger, Dennis D., Greiner, Timothy C., Gascoyne, Randy D., Rosenwald, Andreas, Ott, German, Campo, Elias, Rimsza, Lisa M., Delabie, Jan, Jaffe, Elaine S., Braziel, Rita M., Connors, Joseph M., Wu, Chung-I, Staudt, Louis M., D'Amore, Francesco, McKeithan, Timothy W., Chan, Wing C.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214175/
https://ncbi.nlm.nih.gov/pubmed/27389057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2016.175
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares