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Presentation of antagonist peptides to naive CD4(+) T cells abrogates spatial reorganization of class II MHC peptide complexes on the surface of dendritic cells

By using dendritic cells (DCs) transduced with retroviruses encoding covalent A(b)β/peptide fusion proteins tagged with fluorescent proteins, we followed the relocation of class II MHC molecules loaded with agonist or null peptides during the onset of activation of naive and effector CD4(+) T cells....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chmielowski, Bartosz, Pacholczyk, Rafal, Kraj, Piotr, Kisielow, Pawel, Ignatowicz, Leszek
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2002
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC137536/
https://ncbi.nlm.nih.gov/pubmed/12411579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.222463499
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