p53 expression and K-ras mutation in colorectal adenomas.

The frequency of p53 overexpression and K-ras codon 12 mutation was investigated in a series of colorectal adenomas. p53 was detected by immunohistochemistry in only 5% of tumours, whereas K-ras mutation was found in eight of 30 adenomas examined. In vitro, mutant p53 and ras genes cooperate to tran...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Scott, N, Bell, S M, Sagar, P, Blair, G E, Dixon, M F, Quirke, P
Format: Artigo
Jezik:Inglês
Izdano: 1993
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1374178/
https://ncbi.nlm.nih.gov/pubmed/8504962
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki