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Non-snRNP U1A levels decrease during mammalian B-cell differentiation and release the IgM secretory poly(A) site from repression

A regulated shift from the production of membrane to secretory forms of Immunoglobulin M (IgM) mRNA occurs during B cell differentiation due to the activation of an upstream secretory poly(A) site. U1A plays a key role in inhibiting the expression of the secretory poly(A) site by inhibiting both cle...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: MA, JIANGLIN, GUNDERSON, SAMUEL I., PHILLIPS, CATHERINE
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Copyright 2006 by RNA Society 2006
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370892/
https://ncbi.nlm.nih.gov/pubmed/16373497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2159506
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