Chargement en cours...
Effect of manganese on in vitro replication of damaged DNA catalyzed by the herpes simplex virus type-1 DNA polymerase
In vitro bypass of damaged DNA by replicative DNA polymerases is usually blocked by helix-distorting or bulky DNA lesions. In this study, we report that substitution of the divalent metal ion Mg(2+) with Mn(2+) promotes quantitative replication of model DNA substrates containing the major cisplatin...
Enregistré dans:
| Auteurs principaux: | , , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2002
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC137087/ https://ncbi.nlm.nih.gov/pubmed/12140316 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|