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The replicative DNA polymerase of herpes simplex virus 1 exhibits apurinic/apyrimidinic and 5′-deoxyribose phosphate lyase activities

Base excision repair (BER) is essential for maintaining genome stability both to counter the accumulation of unusual bases and to protect from base loss in the DNA. Herpes simplex virus 1 (HSV-1) is a large dsDNA virus that encodes its own DNA replication machinery, including enzymes involved in nuc...

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Detalhes bibliográficos
Main Authors: Bogani, Federica, Boehmer, Paul E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575316/
https://ncbi.nlm.nih.gov/pubmed/18695225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806375105
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