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Accessory proteins assist exonuclease-deficient bacteriophage T4 DNA polymerase in replicating past an abasic site

Replicative DNA polymerases, such as T4 polymerase, possess both elongation and 3′–5′ exonuclease proofreading catalytic activities. They arrest at the base preceding DNA damage on the coding DNA strand and specialized DNA polymerases have evolved to replicate across the lesion by a process known as...

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Détails bibliographiques
Auteurs principaux: Blanca, Giuseppina, Delagoutte, Emmanuelle, Tanguy le gac, Nicolas, Johnson, Neil P., Baldacci, Giuseppe, Villani, Giuseppe
Format: Artigo
Langue:Inglês
Publié: Portland Press Ltd. 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1798438/
https://ncbi.nlm.nih.gov/pubmed/17064253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060898
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