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Accessory proteins assist exonuclease-deficient bacteriophage T4 DNA polymerase in replicating past an abasic site

Replicative DNA polymerases, such as T4 polymerase, possess both elongation and 3′–5′ exonuclease proofreading catalytic activities. They arrest at the base preceding DNA damage on the coding DNA strand and specialized DNA polymerases have evolved to replicate across the lesion by a process known as...

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Dettagli Bibliografici
Autori principali: Blanca, Giuseppina, Delagoutte, Emmanuelle, Tanguy le gac, Nicolas, Johnson, Neil P., Baldacci, Giuseppe, Villani, Giuseppe
Natura: Artigo
Lingua:Inglês
Pubblicazione: Portland Press Ltd. 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1798438/
https://ncbi.nlm.nih.gov/pubmed/17064253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060898
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