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Nonsense-mediated mRNA decay factors act in concert to regulate common mRNA targets
Nonsense-mediated mRNA decay (NMD) is a surveillance pathway that degrades mRNAs containing nonsense codons, and regulates the expression of naturally occurring transcripts. While NMD is not essential in yeast or nematodes, UPF1, a key NMD effector, is essential in mice. Here we show that NMD compon...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Copyright 2005 by RNA Society
2005
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370837/ https://ncbi.nlm.nih.gov/pubmed/16199763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2160905 |
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