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Structural characterization of an anti-gp120 RNA aptamer that neutralizes R5 strains of HIV-1
We recently described the isolation of 2′-fluoropyrimidine-substituted RNA aptamers that bind specifically to the surface glycoprotein (gp 120) of the R5 strain, HIV-1(Ba-L), as presented in a previous study. These aptamers potently neutralize HIV-1 infectivity in human peripheral blood mononuclear...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Copyright 2005 by RNA Society
2005
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370772/ https://ncbi.nlm.nih.gov/pubmed/15923374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7205405 |
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