Structural definition of a conserved neutralization epitope on HIV-1 gp120

The remarkable diversity, glycosylation and conformational flexibility of the human immunodeficiency virus type 1 (HIV-1) envelope (Env), including substantial rearrangement of the gp120 glycoprotein upon binding the CD4 receptor, allow it to evade antibody-mediated neutralization. Despite this comp...

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Detalhes bibliográficos
Main Authors: Zhou, Tongqing, Xu, Ling, Dey, Barna, Hessell, Ann J., Van Ryk, Donald, Xiang, Shi-Hua, Yang, Xinzhen, Zhang, Mei-Yun, Zwick, Michael B., Arthos, James, Burton, Dennis R., Dimitrov, Dimiter S., Sodroski, Joseph, Wyatt, Richard, Nabel, Gary J., Kwong, Peter D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584968/
https://ncbi.nlm.nih.gov/pubmed/17301785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature05580
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