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Molecular dynamics simulations and free energy calculations of base flipping in dsRNA

The family of adenosine deaminases acting on RNA (ADARs) targets adenosines in RNA that is mainly double stranded. Some substrates are promiscuously deaminated whereas others, such as the mammalian glutamate receptor B (gluR-B) pre-mRNA, are more selectively deaminated. Many DNA/RNA-base modificatio...

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Auteurs principaux: HART, KATARINA, NYSTRÖM, BOEL, ÖHMAN, MARIE, NILSSON, LENNART
Format: Artigo
Langue:Inglês
Publié: Copyright 2005 by RNA Society 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370749/
https://ncbi.nlm.nih.gov/pubmed/15811914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7147805
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