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Stability of 3′ double nucleotide overhangs that model the 3′ ends of siRNA

Thermodynamic parameters are reported for duplex formation in 1 M NaCl for 16 RNA sequences, each containing a core tetramer duplex, GGCC, and a 3′ overhang consisting of two bases. The results indicate additional double-helical stability is conferred by the double 3′ terminal overhang relative to t...

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Hlavní autoři: O’TOOLE, AMANDA S., MILLER, STACY, SERRA, MARTIN J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Copyright 2005 by RNA Society 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370740/
https://ncbi.nlm.nih.gov/pubmed/15769878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7254905
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