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Thermodynamic analysis of 5′ and 3′ single- and 3′ double-nucleotide overhangs neighboring wobble terminal base pairs

Thermodynamic parameters are reported for duplex formation of 40 self-complementary RNA duplexes containing wobble terminal base pairs with all possible 3′ single and double-nucleotide overhangs, mimicking the structures of short interfering RNAs (siRNA) and microRNAs (miRNA). Based on nearest neigh...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Miller, Stacy, Jones, Laura E., Giovannitti, Karen, Piper, Dan, Serra, Martin J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2008
Schlagworte:
RNA
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553593/
https://ncbi.nlm.nih.gov/pubmed/18765476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn525
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