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Activation of the protein kinase PKR by short double-stranded RNAs with single-stranded tails
The human RNA-activated protein kinase PKR is an interferon-induced protein that is part of the innate immune response and inhibits viral replication. The action of PKR involves RNA-dependent autophosphorylation leading to inhibition of translation. PKR has an N-terminal dsRNA-binding domain that ca...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Copyright 2004 by RNA Society
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370682/ https://ncbi.nlm.nih.gov/pubmed/15547138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7150804 |
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